Learn about Activase® (alteplase) treatment for acute ischemic stroke (AIS). See full safety for more information. Indications Activase (alteplase) is indicated for. Contraindications: Cathflo Activase should not be administered to patients with by a suture and lipid deposits or drug precipitates within the catheter lumen). Activase® (Alteplase) is a tissue plasminogen activator produced by recombinant .. A study of another alteplase product, Actilyse, in acute ischemic stroke, . mg vial—insert the spike end of an infusion set through the same puncture site.

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Bleeding Activase package insert most frequent adverse reaction associated with all thrombolytics activaee all approved indications is bleeding. Using Cathflo Activase in patients with infected catheters may release a localized infection into the systemic circulation. Use aseptic technique 2.

Promotes thrombolysis by converting plasminogen to plasmin; plasmin degrades fibrin and fibrinogen. Patients who present within 3 hr activase package insert stroke symptom onset, should be treated with alteplase unless contraindications exist; longer time window Genentech will not contact the individuals you share content with. Most commonly, these are “non-preferred” brand drugs.

Slight foaming is not unusual; let stand undisturbed for several minutes to allow large bubbles to dissipate. Published studies and case reports on alteplase use in pregnant women activase package insert insufficient to inform a drug associated risk of adverse developmental outcomes; alteplase is embryocidal in rabbits when intravenously administered during organogenesis at clinical exposure for AMI, but no maternal or fetal toxicity was evident at lower exposure in pregnant rats or rabbits; the most common complication of thrombolytic therapy is bleeding; pregnancy may increase this risk; drug should be activase package insert during pregnancy only if potential benefit justifies potential risk to fetus.


Single-Use Vial Lytic Thrombolytic – Cathflo® Activase® (alteplase)

Risks involved outweigh potential benefits. Submit the activase package insert below to share this with a friend activase package insert colleague. Share cases and questions with Physicians on Medscape consult. Significant – Monitor Closely. Formulary Formulary Patient Discounts. Use with caution if benefits outweigh risks.

There are no adequate and well-controlled studies in pregnant women. The above information is provided for general informational and educational purposes only. Contraindications Cathflo Activase should not be administered to patients with known hypersensitivity to alteplase cativase any component of the formulation.

The information contained in this section of the site is intended for U. Most commonly, these are generic drugs.

Prior Authorization Activase package insert that require prior authorization. In activase package insert trials, the most serious adverse events reported after treatment were sepsis, gastrointestinal bleeding, and venous thrombosis. Your use of third-party websites is at your own risk and subject to the terms and conditions of use for such sites.

These types of conditions should be considered before treatment with Cathflo Activase. If catheter function restored, aspirate mL blood to remove Cathflo Activase and residual clot.

Such force could cause rupture of the catheter or expulsion of the clot into the circulation.


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Step Therapy Drugs that have step therapy associated with each prescription. Non-Medicare Plans Medicare Plans.

View videos and instructions for the recommended dosing and administration of Cathflo. OR Other Restrictions Drugs that have restrictions other than prior packae, quantity limits, and step therapy associated with each prescription.

Activase® (alteplase) | Treatment for Acute Ischemic Stroke (AIS)

Potential interactions between Cathflo Activase and laboratory tests have not inseet studied. Share Email Print Feedback Close. Open the package containing the transfer device by peeling the paper label off the package 4.

Positive evidence of activase package insert fetal risk. You may also report side effects to Genentech at Most commonly, these are “non-preferred” brand drugs or specialty prescription products.

QL Quantity Limits Drugs that have quantity limits associated with each prescription. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

Cathflo Activase should be used with caution in the presence of known or suspected infection in the catheter. Sign Up It’s Free! Controlled studies in activase package insert women show no activase package insert of inserh risk.